Evaluation and optimization of combined gum mixture as matrix former biomaterial in drug delivery

dc.contributor.author	Singh, Akhilesh V.	en
dc.date.accessioned	2015-02-02T07:28:58Z
dc.date.available	2015-02-02T07:28:58Z
dc.date.issued	2015-02-02
dc.identifier.uri	http://hdl.handle.net/11400/5415
dc.rights	Αναφορά Δημιουργού-Μη Εμπορική Χρήση-Όχι Παράγωγα Έργα 3.0 Ηνωμένες Πολιτείες	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/3.0/us/	*
dc.source	http://e-jst.teiath.gr/	en
dc.subject	Diclofenac sodium
dc.subject	Νατριούχος δικλοφενάκη
dc.subject	Ghatti gum
dc.subject	Konjac glucomannan
dc.subject	FT-IR
dc.subject	Γλυκομαννάνη Konjac
dc.title	Evaluation and optimization of combined gum mixture as matrix former biomaterial in drug delivery	en
heal.type	journalArticle
heal.classification	Medicine
heal.classification	Pharmacy
heal.classification	Ιατρική
heal.classification	Φαρμακευτική
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh00006614
heal.classificationURI	N/A-Pharmacy
heal.classificationURI	N/A-Ιατρική
heal.classificationURI	N/A-Φαρμακευτική
heal.language	en
heal.access	free
heal.publicationDate	2011
heal.bibliographicCitation	Singh, A.V. (2011). Evaluation and optimization of combined gum mixture as matrix former biomaterial in drug delivery. "e-Journal of Science & Technology". [Online] 6(2): 95-99. Available from: http://e-jst.teiath.gr/	en
heal.abstract	In the present investigation, two novel gum mixtures were evaluated as controlled release polymer. The ghatti gum obtained from Anogeissus latifolia and Konjac glucomannan from Amorphophallus konjac was evaluated as base polymer for controlled delivery of model drug diclofenac sodium. The prepared synergistically acting gums were evaluated for compatibility study using FT-IR. The diclofenac sodium tablets were evaluated for hardness, friability, weight variation and drug content. The in vitro dissolution study confirmed that the controlled release behavior is mainly due to konjac glucomannan proportion and optimum concentration ratio for ghatti: konjac glucomannan was 30:70.	en
heal.publisher	Νερατζής, Ηλίας	el
heal.publisher	Σιανούδης, Ιωάννης	el
heal.journalName	e-Journal of Science & Technology	en
heal.journalName	e-Περιοδικό Επιστήμης & Τεχνολογίας	el
heal.journalType	peer-reviewed
heal.fullTextAvailability	true